Heat a large skillet over medium heat. Add olive oil and warm it up. Sauté diced onion for 3-4 minutes until soft and translucent. Add minced garlic and ground beef, cooking for 5-7 minutes until browned. Drain excess fat if necessary.
Stir in Cajun seasoning, smoked paprika, black pepper, and salt. Mix well. Lower heat and add softened cream cheese, stirring until melted. Slowly pour in heavy cream while stirring until smooth. Add grated Parmesan cheese and stir until melted.
Cook bowtie pasta in a large pot of salted boiling water according to package instructions until al dente, about 8-10 minutes. Drain and set aside without rinsing.
Toss cooked bowtie pasta into the skillet with the sauce, mixing gently to coat. If sauce is too thick, add a splash of pasta water to loosen it. Adjust seasoning if needed.
Remove from heat, transfer to serving plates or a bowl, and garnish with chopped parsley. Serve immediately.